Asclepias amplexicaulis, commonly known as clasping milkweed, thrives in intact habitats such as prairies, savannas, and open woods, where it benefits from full sun and well-drained soils. This perennial plant grows robustly, reaching heights of 2 to 3 feet, with distinctive clasping leaves that wrap around the stem. It typically blooms from late spring to early summer, producing clusters of small, fragrant flowers that attract a variety of pollinators, including bees and butterflies. The presence of Asclepias amplexicaulis in these ecosystems contributes to biodiversity and supports the life cycles of numerous insects, making it an important component of its native habitat.